PXD025883 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | LC-MS/MS analysis of NGF proteins purified from cerebrospinal fluid |
Description | The aim of the project is to develop and validate a new method to measure proNGF in the cerebrospinal fluid of living patients, and to use it as a biomarker of Alzheimer’s disease (AD). This method, a novel proNGF immunoassay, is based on molecular size separation by capillary electrophoresis and is performed with Simple Wes: this technique produces different immunoreactive peaks whose area can be calculated to search for a quantitative relation with AD. Our purpose was to confirm and validate by mass spectrometry analysis the presence of NGF in the selected peaks |
HostingRepository | PRIDE |
AnnounceDate | 2022-02-17 |
AnnouncementXML | Submission_2022-02-17_03:11:48.825.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD025883 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Serena Camerini |
SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-05-07 09:46:19 | ID requested | |
⏵ 1 | 2022-02-17 03:11:49 | announced | |
Publication List
Malerba F, Arisi I, Florio R, Zecca C, Dell'Abate MT, Bruni Ercole B, Camerini S, Casella M, Logroscino G, Cattaneo A, proNGF Measurement in Cerebrospinal Fluid Samples of a Large Cohort of Living Patients With Alzheimer's Disease by a New Automated Immunoassay. Front Aging Neurosci, 13():741414(2021) [pubmed] |
Keyword List
submitter keyword: NGF, Alzheimer, cerebrospinal fluid, mass spectrometry |
Contact List
Serena Camerini |
contact affiliation | Istituto superiore di Sanità |
contact email | Serena.camerini@iss.it |
lab head | |
Serena Camerini |
contact affiliation | Istituto superiore di sanità |
contact email | serena.camerini@iss.it |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD025883 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD025883
- Label: PRIDE project
- Name: LC-MS/MS analysis of NGF proteins purified from cerebrospinal fluid