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PXD025861

PXD025861 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCharacterisation of a FAK-proximal nuclear interactome
DescriptionIn addition to central functions in cell adhesion signalling, integrin-associated proteins have wider roles at sites distal to adhesion receptors. In experimentally defined adhesomes, we noticed that there is clear enrichment of proteins that localise to the nucleus, and conversely, we now report that nuclear proteomes contain a class of adhesome components that localise to the nucleus. We here defined a FAK-proximal subproteome that localises to the nucleus.
HostingRepositoryPRIDE
AnnounceDate2022-06-01
AnnouncementXMLSubmission_2022-06-01_02:32:28.362.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAdam Byron
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList2-pyrrolidone-5-carboxylic acid (Gln); biotinylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-05-07 04:20:55ID requested
12022-06-01 02:32:28announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: human, nucleus, adhesion, FAK
Contact List
Margaret Frame
contact affiliationUniversity of Edinburgh
contact emailm.frame@ed.ac.uk
lab head
Adam Byron
contact affiliationUniversity of Edinburgh
contact emailadam.byron@igmm.ed.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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