PXD025800

PXD025800 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Integrative multi-omics analysis in sepsis-associated liver dysfunction
Description	we conducted integrative multiple levels of omics data including transcriptome, phosphoproteome, proteome and metabolome in different time-course of sepsis-associated liver dysfunction (SALD). This is the first trial to suggest the statistical pathway of integrative multi-omics data in sepsis. Given the increasing number of studies collecting multi-omics data but limited overview of the methodological framework for integrative analyses (Liu, Ding et al. 2013, Petersen, Zeilinger et al. 2014, Shah, Bonder et al. 2015), integrative approach in sepsis with liver dysfunction in this study will provide novel insights into the development of sepsis and ultimately offer new tools for overcoming the present diagnostic limitation. Therefore, a combined multi-omics dataset will give better accessibility of adoption in disease, and insight to identify the promising candidates for therapeutic strategies.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:49:20.450.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ann-Yae Na
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-05 01:53:51	ID requested
1	2023-06-20 23:09:28	announced
2	2023-11-14 09:01:35	announced	2023-11-14: Updated project metadata.
⏵ 3	2024-10-22 05:49:21	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/j.gpb.2023.04.002;
Na AY, Lee H, Min EK, Paudel S, Choi SY, Sim H, Liu KH, Kim KT, Bae JS, Lee S, Novel Time-dependent Multi-omics Integration in Sepsis-associated Liver Dysfunction. Genomics Proteomics Bioinformatics, 21(6):1101-1116(2023) [pubmed]

10.1016/j.gpb.2023.04.002;

Na AY, Lee H, Min EK, Paudel S, Choi SY, Sim H, Liu KH, Kim KT, Bae JS, Lee S, Novel Time-dependent Multi-omics Integration in Sepsis-associated Liver Dysfunction. Genomics Proteomics Bioinformatics, 21(6):1101-1116(2023) [pubmed]

Keyword List

ProteomeXchange project tag: Toxicoproteomics (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: sepsis, liver dysfunction,multiomics,integrative omics

ProteomeXchange project tag: Toxicoproteomics (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: sepsis, liver dysfunction,multiomics,integrative omics

Contact List

Sangkyu Lee
contact affiliation	Kyungpook national university
contact email	pharm239@gmail.com
lab head
Ann-Yae Na
contact affiliation	kyungpook national university
contact email	cpblady@hanmail.net
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD025800
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/06/PXD025800

PRIDE project URI

Repository Record List

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