PXD025773

PXD025773 is an original dataset announced via ProteomeXchange.

Title	Proteomic response of rat hippocampus under chronic unpredicted mild stress reveals insights into susceptibility and insensitivity to depression
Description	We used a chronic unpredicted mild stress (CUMS) protocol to separate depression-susceptible and stress-insensitive rat subgroups. Differential proteomes in the hippocampus were analyzed based on isobaric tags for relative and absolute quantitation (iTRAQ) labeling combined with mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_03:04:17.911.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qing Tian
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-05-03 23:06:04	ID requested
⏵ 1	2022-02-17 03:04:18	announced

Zhang T, Yang C, Chu J, Ning LN, Zeng P, Wang XM, Shi Y, Qin BJ, Qu N, Zhang Q, Tian Q, Emodin Prevented Depression in Chronic Unpredicted Mild Stress-Exposed Rats by Targeting miR-139-5p/5-Lipoxygenase. Front Cell Dev Biol, 9():696619(2021) [pubmed]

submitter keyword: depression, chronic unpredicted mild stress, hippocampus, proteome

Qing Tian
contact affiliation	Department of Pathology and Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
contact email	zhangteng012@hust.edu.cn
lab head
Qing Tian
contact affiliation	Tongji Medical College, Huazhong University of Science and Technology
contact email	zhangteng012@hust.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD025773

PRIDE project URI

• PRIDE
  1. PXD025773
     1. Label: PRIDE project
     2. Name: Proteomic response of rat hippocampus under chronic unpredicted mild stress reveals insights into susceptibility and insensitivity to depression