PXD025703

PXD025703 is an original dataset announced via ProteomeXchange.

Title	Famotidine targets Toll-like receptor 3 signaling in SARS-CoV2 infection
Description	Caco2 cells were pretreated with 100µM histamine and 50µM Famotidine for 12h followed by infection with SARS-CoV2 for 24h. After that proteome was analysed.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_03:00:43.217.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Anshu Bhattacharya
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-29 01:33:33	ID requested
⏵ 1	2022-02-17 03:00:44	announced

Mukherjee R, Bhattacharya A, Bojkova D, Mehdipour AR, Shin D, Khan KS, Hei-Yin Cheung H, Wong KB, Ng WL, Cinatl J, Geurink PP, van der Heden van Noort GJ, Rajalingam K, Ciesek S, Hummer G, Dikic I, Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection. J Biol Chem, 297(2):100925(2021) [pubmed]

submitter keyword: Famotidine, Toll-like receptor, SARS-CoV2, anti-viral signaling, histamine

Ivan Dikic
contact affiliation	Institue of Biochemistry 2, Buchmann institute for Molecular Life Sciences
contact email	dikic@med.uni-frankfurt.de
lab head
Anshu Bhattacharya
contact affiliation	Goethe University, Institute of Biochemistry 2, Buchmann Institute For Molecular Life Sciences
contact email	bhattacharya@med.uni-frankfurt.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD025703

PRIDE project URI

• PRIDE
  1. PXD025703
     1. Label: PRIDE project
     2. Name: Famotidine targets Toll-like receptor 3 signaling in SARS-CoV2 infection