PXD025678

PXD025678 is an original dataset announced via ProteomeXchange.

Title	Rat heterotopic ossification model proteome
Description	The mechanism of heterotopic ossification remains largely unclarified. in this project, we administrated Achilles tenotomy (AT) and partial Achilles tenotomy (PAT) to rat models to simulate the varied size of ectopic bone we observed in the clinical courses. Then we applied Data-independent acquisition (DIA) proteomic strategy to identify the proteins and signaling pathways associated with the progress of heterotopic ossification and propagation of the ectopic bone mass.
HostingRepository	iProX
AnnounceDate	2021-04-28
AnnouncementXML	Submission_2022-11-09_23:20:29.858.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Biao Zhong
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive; Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-28 00:03:35	ID requested
⏵ 1	2022-11-09 23:20:30	announced

Wei Z, Guo S, Wang H, Zhao Y, Yan J, Zhang C, Zhong B, Comparative proteomic analysis identifies differentially expressed proteins and reveals potential mechanisms of traumatic heterotopic ossification progression. J Orthop Translat, 34():42-59(2022) [pubmed]

submitter keyword: Rat, heterotopic ossification model, proteome

Biao Zhong
contact affiliation	Shanghai Jiao Tong university Affiliated Sixth People's Hospital
contact email	biao.zhong@sjtu.edu.cn
lab head
Biao Zhong
contact affiliation	Shanghai Jiao Tong university Affiliated Sixth People's Hospital
contact email	biao.zhong@sjtu.edu.cn
dataset submitter

iProX dataset URI