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PXD025666

PXD025666 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhysiological Characterization of Adaptive Evolutionary Dynamics
DescriptionLong-term laboratory evolution experiments provide a controlled record of evolutionary dynamics and metabolic change in microorganisms. Nevertheless, the correspondence between genetic mutation and phenotypic adaptation remains elusive, partly because of the overwhelming number of genetic changes that accrue after tens-of-thousands of generations. Using a coarse-grained characterization of bacterial physiology applied to Lenski's laboratory-evolved strains of Escherichia coli, we identify an intermediate measure between genotype and phenotype that provides insight into the dynamics of adaptation.
HostingRepositoryMassIVE
AnnounceDate2024-04-12
AnnouncementXMLSubmission_2024-04-12_12:20:03.604.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterVadim Patsalo
SpeciesList scientific name: Escherichia coli BL21; NCBI TaxID: 511693;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-27 11:34:19ID requested
12024-04-12 12:20:04announced
Publication List
no publication
Keyword List
submitter keyword: escherichiaColi, Lenski, evolution, adaptation, growth laws, physiology
Contact List
Matthew Scott
contact affiliationUniversity of Waterloo
contact emailmscott@uwaterloo.ca
lab head
James R. Williamson
contact affiliationThe Scripps Research Institute
contact emailjrwill@scripps.edu
lab head
Vadim Patsalo
contact affiliationScripps Research
contact emailpatsalov@gmail.com
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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