PXD025560
PXD025560 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human NSCLC DIA proteomics validation cohort 2 |
Description | In this project, one NSCLC cohorts were analyzed by Data Independent Acquisition (DIA-MS). A cohort of early stage NSCLC samples (207) with the aim to demonstrate utility of MS for subtyping and treatment prediction in a clinical setting. Further, six identified NSCLC proteome subtypes were investigated in relation to cancer driver pathways and immune phenotypes based on the generated MS-data. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-13 |
AnnouncementXML | Submission_2022-01-19_06:31:05.053.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Georgios Mermelekas |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-04-22 06:22:16 | ID requested | |
1 | 2021-09-13 07:54:30 | announced | |
⏵ 2 | 2022-01-19 06:31:07 | announced | 2022-01-19: Updated publication reference for PubMed record(s): 34870237. |
Publication List
Lehti, ö J, Arslan T, Siavelis I, Pan Y, Socciarelli F, Berkovska O, Umer HM, Mermelekas G, Pirmoradian M, J, ö, nsson M, Brunnstr, ö, m H, Brustugun OT, Purohit KP, Cunningham R, Foroughi Asl H, Isaksson S, Arbajian E, Aine M, Karlsson A, Kotevska M, Gram Hansen C, Drageset Haakensen V, Helland Å, Tamborero D, Johansson HJ, Branca RM, Planck M, Staaf J, Orre LM, Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms. Nat Cancer, 2(11):1224-1242(2021) [pubmed] |
Keyword List
submitter keyword: lung cancer, DIA, classification, adenocarcinoma, mass spectrometry |
Contact List
Janne Lehtiö | |
---|---|
contact affiliation | Karolinska Institutet, Oncology and pathology department, Stockholm, Sweden |
contact email | janne.lehtio@ki.se |
lab head | |
Georgios Mermelekas | |
contact affiliation | Karolinska Institutet |
contact email | georgios.mermelekas@scilifelab.se |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD025560 |
PRIDE project URI |
Repository Record List
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