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PXD025527

PXD025527 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComprehensive proteomics for Discovery vaccine candidates against Streptococcus equi Infections
DescriptionStreptococcus equi subspecies equi (S. equi) is a major pathogen which cause strangles, a highly contagious respiratory infection, in horses and other equines. In this study, we purified the extracellular vesicles (EVs) of S. equi ATCC 39506 and evaluated them as vaccine candidates against S. equi infections in mice. Through immunization in an animal model and immunoprecipitation-mass spectrometry, we evaluated EV as vaccine candidates against S. equi infections and identified novel immunogenic proteins.
HostingRepositoryPRIDE
AnnounceDate2021-08-06
AnnouncementXMLSubmission_2021-08-06_02:06:05.188.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD025527
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterHayoung Lee
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Streptococcus equi subsp. equi; NCBI TaxID: 148942;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-21 03:40:25ID requested
12021-08-05 17:26:47announced
22021-08-06 02:06:05announced2021-08-06: Updated project metadata.
Publication List
Lee H, Yun SH, Hyon JY, Lee SY, Yi YS, Choi CW, Jun S, Park EC, Kim SI, Streptococcus equi-derived extracellular vesicles as a vaccine candidate against Streptococcus equi infection. Vet Microbiol, 259():109165(2021) [pubmed]
10.1016/J.VETMIC.2021.109165;
Keyword List
submitter keyword: Label-free, LC-MS,Streptococcus equi, Extracellular Vesicle, Immunoprecipitation-MS
Contact List
Seung Il Kim
contact affiliationResearch Center for Bioconvergence Analysis, 458 Korea Basic Science Institute, Ochang 28119, Korea Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea
contact emailksi@kbsi.re.kr
lab head
Hayoung Lee
contact affiliationKorea basic science institute
contact emailbiryu32@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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