PXD025527 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Comprehensive proteomics for Discovery vaccine candidates against Streptococcus equi Infections |
Description | Streptococcus equi subspecies equi (S. equi) is a major pathogen which cause strangles, a highly contagious respiratory infection, in horses and other equines. In this study, we purified the extracellular vesicles (EVs) of S. equi ATCC 39506 and evaluated them as vaccine candidates against S. equi infections in mice. Through immunization in an animal model and immunoprecipitation-mass spectrometry, we evaluated EV as vaccine candidates against S. equi infections and identified novel immunogenic proteins. |
HostingRepository | PRIDE |
AnnounceDate | 2021-08-06 |
AnnouncementXML | Submission_2021-08-06_02:06:05.188.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD025527 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Hayoung Lee |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Streptococcus equi subsp. equi; NCBI TaxID: 148942; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-04-21 03:40:25 | ID requested | |
1 | 2021-08-05 17:26:47 | announced | |
⏵ 2 | 2021-08-06 02:06:05 | announced | 2021-08-06: Updated project metadata. |
Publication List
Lee H, Yun SH, Hyon JY, Lee SY, Yi YS, Choi CW, Jun S, Park EC, Kim SI, Streptococcus equi-derived extracellular vesicles as a vaccine candidate against Streptococcus equi infection. Vet Microbiol, 259():109165(2021) [pubmed] |
10.1016/J.VETMIC.2021.109165; |
Keyword List
submitter keyword: Label-free, LC-MS,Streptococcus equi, Extracellular Vesicle, Immunoprecipitation-MS |
Contact List
Seung Il Kim |
contact affiliation | Research Center for Bioconvergence Analysis, 458 Korea Basic Science Institute, Ochang 28119, Korea Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea |
contact email | ksi@kbsi.re.kr |
lab head | |
Hayoung Lee |
contact affiliation | Korea basic science institute |
contact email | biryu32@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD025527
- Label: PRIDE project
- Name: Comprehensive proteomics for Discovery vaccine candidates against Streptococcus equi Infections