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PXD025520

PXD025520 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe interactome of Zbtb2 in mouse embryonic stem cells
DescriptionZbtb2 is a transcription factor that plays a role in mouse embryonic stem cell (mESC) differentiation. We pulled-down endogenously tagged Zbtb2-FLAG in mESCs and found a complex interactome. We characterized the Zbtb2 complex further by co-pull-downs of overexpressed Zbtb2-AVI, after mutation of individual Zbtb2 domains or of complex subunits, as well as by taking advantage of a tagged construct displaying dominant negative activity (Zbtb2-HAF).
HostingRepositoryPRIDE
AnnounceDate2021-07-14
AnnouncementXMLSubmission_2021-07-13_21:50:08.521.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDaniel Hess
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-21 02:43:08ID requested
12021-07-13 21:50:08announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Zbtb2 interactome, mouse embryonic stem cells, development
Contact List
Jörg Betschinger
contact affiliationFriedrich Miescher Institute for BiomedicalResearch, Basel, Switzerland
contact emailjoerg.betschinger@fmi.ch
lab head
Daniel Hess
contact affiliationFriedrich Miescher Institute for Biomedical Research
contact emaildhess@fmi.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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