PXD025486

PXD025486 is an original dataset announced via ProteomeXchange.

Title	Mouse brain MALDI-imaging proteomics profiling
Description	We developed and validated ‘HIT-MAP’ (High-resolution Informatics Toolbox in MALDI-MSI Proteomics), an open-source bioinformatics workflow using peptide mass fingerprint analysis and a dual scoring system to computationally assign peptide and protein annotations to high mass resolution MSI datasets, and generate customisable spatial distribution maps. The uploaded files are an example dataset for the HiTMaP proteomics search engine, designed for MALDI-imaging proteomics annotation. The example data files contain one bovine lens tissue section and one mouse brain tissue section. The ID folder contains the protein/peptide identification result for each tissue segment, and the summary folder contains the protein cluster images.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:21:57.341.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	George, G GUO
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	No PTMs are included in the dataset
Instrument	Bruker Daltonics solarix series

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-20 02:16:11	ID requested
1	2021-05-16 17:50:15	announced
2	2021-07-19 23:22:48	announced	2021-07-20: Updated publication reference for PubMed record(s): 34050164.
⏵ 3	2024-10-22 05:21:59	announced	2024-10-22: Updated project metadata.

Guo G, Papanicolaou M, Demarais NJ, Wang Z, Schey KL, Timpson P, Cox TR, Grey AC, Automated annotation and visualisation of high-resolution spatial proteomic mass spectrometry imaging data using HIT-MAP. Nat Commun, 12(1):3241(2021) [pubmed]

10.1038/s41467-021-23461-w;

submitter keyword: Mouse brain, proteomics, bovin lens, MALDI-imaging

GUS GREY
contact affiliation	Department of Physiology, the University of Auckland
contact email	ac.grey@auckland.ac.nz
lab head
George, G GUO
contact affiliation	The University of Auckland
contact email	guoguodigital@msn.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/05/PXD025486

PRIDE project URI

• PRIDE
  1. PXD025486
     1. Label: PRIDE project
     2. Name: Mouse brain MALDI-imaging proteomics profiling