PXD025471

PXD025471 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A synthetic protein as efficient multitarget regulator against complement over-activation
Description	Here we report the production of MFHR13, a synthetic multitarget complement regulator produced in the moss Physcomitrella. MFHR13 combines the dimerization and C5-regulatory domains of human FH-related protein 1 (FHR1) with the C3-regulatory and host-cell surface recognition domains of human FH, including SCR13.
HostingRepository	PRIDE
AnnounceDate	2024-04-17
AnnouncementXML	Submission_2024-04-17_00:16:23.893.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD025471
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ralf Reski
SpeciesList	scientific name: Physcomitrella; NCBI TaxID: 3217;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-19 06:31:33	ID requested
⏵ 1	2024-04-17 00:16:24	announced

Publication List

10.1038/S42003-022-03094-5;
10.6019/PXD025471;

10.1038/S42003-022-03094-5;

10.6019/PXD025471;

Keyword List

submitter keyword: Synthetic complement regulator, Physcomitrella, biopharmaceutical, MFHR13, factor H

submitter keyword: Synthetic complement regulator, Physcomitrella, biopharmaceutical, MFHR13, factor H

Contact List

Ralf Reski
contact affiliation	Plant Biotechnology, Faculty of Biology, University of Freiburg, Schaenzlestr.1, D-79104 Freiburg, Germany
contact email	ralf.reski@biologie.uni-freiburg.de
lab head
Ralf Reski
contact affiliation	Faculty of Biology, University of Freiburg (Chair Plant Biotechnology), Schaenzlestr. 1, D-79104 Freiburg
contact email	ralf.reski@biologie.uni-freiburg.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD025471
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD025471

PRIDE project URI

Repository Record List

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