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PXD025463

PXD025463 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleGel-based proteomics of Sjögren’s Syndrome patient saliva
DescriptionSjögren's Syndrome (SS) is an autoimmune exocrinopathy characterized by the progressive damage of salivary and lacrimal glands associated with lymphocytic infiltration. It can be defined as primary SS (pSS) or associated/secondary SS (sSS) if combined with another systemic autoimmune disease. Identifying new non-invasive biomarkers for SS diagnosis remains a challenge, and alterations in saliva composition reported in patients turn this fluid into a source of potential biomarkers. To examine the overall panorama of proteins in saliva, samples of control, pSS, and sSS individuals were analyzed by gel-based LC-MS/MS.
HostingRepositoryPRIDE
AnnounceDate2021-06-09
AnnouncementXMLSubmission_2021-06-08_22:43:56.075.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSEBASTIEN CHARNEAU
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-19 01:31:56ID requested
12021-06-08 22:43:56announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Saliva, Sjögren’s Syndrome, gel-free, SDS-PAGE, primary SS, secondary SS, SDS-PAGE
Contact List
Sébastien Charneau
contact affiliationLaboratory of Protein Chemistry and Biochemistry, Institute of Biology, Department of Cell Biology, University of Brasília, Brasília, Brazil
contact emailcharneau@unb.br
lab head
SEBASTIEN CHARNEAU
contact affiliationUNIVERSITY OF BRASILIA
contact emailcharneau@unb.br
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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