PXD025460

PXD025460 is an original dataset announced via ProteomeXchange.

Title	proteomic analysis of membrane vesicles from clinical Cutibacterium acnes isolates
Description	Recently the membrane vesicles (MVs) production has been observed in Gram-positive bacterium, Cutibacterium acnes (C. acnes). In order to explore the mechanism of antibiotic resistance and the virulent components within the C. acnes-derived MVs, we isolated MVs from the clinical C. acnes, which were sensitive or resistant to antibiotics erythromycin and clindamycin. With the LC-MS/MS method, we detected several lipases, virulent factors and cell division protein differentially expressed between the sensitive and the resistant C. acnes-derived MVs.
HostingRepository	PRIDE
AnnounceDate	2022-05-20
AnnouncementXML	Submission_2022-05-19_22:41:54.266.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Min Jiang
SpeciesList	scientific name: Cutibacterium acnes SK137; NCBI TaxID: 553199;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-19 00:21:12	ID requested
⏵ 1	2022-05-19 22:41:55	announced

Jiang M, Fan X, Jiang Z, Chen H, Liu Y, Yu T, Huang Q, Ma Y, Isolates with Differential Antibiotic Resistance. Clin Cosmet Investig Dermatol, 15():703-712(2022) [pubmed]

submitter keyword: C. acnes, membrane vesicles, LC-MS/MS

Ying Ma
contact affiliation	Department of Dermatology, Huashan Hospital, Fudan University, No.12 Wulumuqizhong Road, Shanghai 200040, China.
contact email	alle_ma@163.com
lab head
Min Jiang
contact affiliation	Department of Dermatology, Huashan Hospital, Fudan University
contact email	fmm1243@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD025460

PRIDE project URI

• PRIDE
  1. PXD025460
     1. Label: PRIDE project
     2. Name: proteomic analysis of membrane vesicles from clinical Cutibacterium acnes isolates