PXD025398

PXD025398 is an original dataset announced via ProteomeXchange.

Title	Identification of CARP3-interacting proteins in Trypanosoma brucei bloodstream forms and procyclic forms
Description	How flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. The trypanosome-specific cAMP response protein 3 (CARP3) shows developmentally regulated localization at the flagellar tip membrane, where it is essential for parasite swarming and colonization of the tsetse fly insect vector. This project describes identification of CARP3-YFP interacting proteins by GFP trap pull down followed by mass spectrometry in the bloodstream stage as well as in the procyclic stage of Trypanosoma brucei.
HostingRepository	PRIDE
AnnounceDate	2022-08-31
AnnouncementXML	Submission_2022-08-31_10:48:41.381.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ignasi Forne
SpeciesList	scientific name: Trypanosoma brucei brucei; NCBI TaxID: 5702;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-14 06:11:12	ID requested
⏵ 1	2022-08-31 10:48:41	announced

Dataset with its publication pending

submitter keyword: cAMP response protein, CARP3, adenylate cyclase, cyclase-interacting protein, GFP trap

Boshart, Michael
contact affiliation	Biocenter, Faculty of Biology, Genetics Ludwig-Maximilians-University Munich (LMU) 82152 Martinsried, Germany
contact email	boshart@lmu.de
lab head
Ignasi Forne
contact affiliation	Biomedical Center-LMU
contact email	ignasi.forne@lrz.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD025398

PRIDE project URI

• PRIDE
  1. PXD025398
     1. Label: PRIDE project
     2. Name: Identification of CARP3-interacting proteins in Trypanosoma brucei bloodstream forms and procyclic forms