PXD025364

PXD025364 is an original dataset announced via ProteomeXchange.

Title	HSP70-driven molecular response to the proteasome machinery inhibition is a vulnerability in cancer
Description	Cell lines indicated in the file names were either treated with carfilzomib (C) at concentrations near the IC50 of proteasome activity in each cell line for 24h, or with DMSO (D) as a control, in biological duplicates.
HostingRepository	PRIDE
AnnounceDate	2025-10-29
AnnouncementXML	Submission_2025-10-29_10:08:57.851.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jacek Wisniewski
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	phosphorylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-13 02:13:06	ID requested
⏵ 1	2025-10-29 10:08:58	announced

10.1016/J.CELREP.2022.111428;

submitter keyword: Human, Cancer, HSP70

Jacek R Wisniewski
contact affiliation	MPI f. Biochemie, Martinsried, Germany
contact email	jwisniew@biochem.mpg.de
lab head
Jacek Wisniewski
contact affiliation	Proteomics
contact email	jwisniew@biochem.mpg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD025364

PRIDE project URI

• PRIDE
  1. PXD025364
     1. Label: PRIDE project
     2. Name: HSP70-driven molecular response to the proteasome machinery inhibition is a vulnerability in cancer