PXD025357 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | BioID-based proteomic analysis of CARP3-proximal proteins in Trypanosoma brucei bloodstream forms |
Description | How flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. The trypanosome-specific cAMP response protein 3 (CARP3) shows developmentally regulated localization at the flagellar tip membrane, where it is essential for parasite swarming and colonization of the tsetse fly insect vector. This project describes a proximity-dependent proteomics approach (BioID) that identified proteins in close vicinity of CARP3 in the bloodstream stage of Trypanosoma brucei. |
HostingRepository | PRIDE |
AnnounceDate | 2022-08-17 |
AnnouncementXML | Submission_2022-08-17_01:21:28.459.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Dupuy Jean-William |
SpeciesList | scientific name: Trypanosoma brucei; NCBI TaxID: 5691; |
ModificationList | biotinylated residue; acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-04-12 23:47:26 | ID requested | |
⏵ 1 | 2022-08-17 01:21:28 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: cAMP response protein, CARP3, adenylate cyclase, cyclase-interacting protein, flagellar member 8, FLAM8 |
Contact List
Michael Boshart |
contact affiliation | Biocenter, Faculty of Biology, Genetics, Ludwig-Maximilians-University Munich (LMU), 82152 Martinsried, Germany |
contact email | boshart@lrz.uni-muenchen.de |
lab head | |
Dupuy Jean-William |
contact affiliation | Plateforme Proteome Bordeaux |
contact email | jean-william.dupuy@u-bordeaux.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD025357 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD025357
- Label: PRIDE project
- Name: BioID-based proteomic analysis of CARP3-proximal proteins in Trypanosoma brucei bloodstream forms