PXD025357

PXD025357 is an original dataset announced via ProteomeXchange.

Title	BioID-based proteomic analysis of CARP3-proximal proteins in Trypanosoma brucei bloodstream forms
Description	How flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. The trypanosome-specific cAMP response protein 3 (CARP3) shows developmentally regulated localization at the flagellar tip membrane, where it is essential for parasite swarming and colonization of the tsetse fly insect vector. This project describes a proximity-dependent proteomics approach (BioID) that identified proteins in close vicinity of CARP3 in the bloodstream stage of Trypanosoma brucei.
HostingRepository	PRIDE
AnnounceDate	2022-08-17
AnnouncementXML	Submission_2022-08-17_01:21:28.459.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dupuy Jean-William
SpeciesList	scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationList	biotinylated residue; acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-12 23:47:26	ID requested
⏵ 1	2022-08-17 01:21:28	announced

Dataset with its publication pending

submitter keyword: cAMP response protein, CARP3, adenylate cyclase, cyclase-interacting protein, flagellar member 8, FLAM8

Michael Boshart
contact affiliation	Biocenter, Faculty of Biology, Genetics, Ludwig-Maximilians-University Munich (LMU), 82152 Martinsried, Germany
contact email	boshart@lrz.uni-muenchen.de
lab head
Dupuy Jean-William
contact affiliation	Plateforme Proteome Bordeaux
contact email	jean-william.dupuy@u-bordeaux.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD025357

PRIDE project URI

• PRIDE
  1. PXD025357
     1. Label: PRIDE project
     2. Name: BioID-based proteomic analysis of CARP3-proximal proteins in Trypanosoma brucei bloodstream forms