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PXD025357

PXD025357 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleBioID-based proteomic analysis of CARP3-proximal proteins in Trypanosoma brucei bloodstream forms
DescriptionHow flagellar signaling regulates the host interaction of parasites remains a challenge due to poor conservation of signaling systems with those in cilia of higher organisms. The trypanosome-specific cAMP response protein 3 (CARP3) shows developmentally regulated localization at the flagellar tip membrane, where it is essential for parasite swarming and colonization of the tsetse fly insect vector. This project describes a proximity-dependent proteomics approach (BioID) that identified proteins in close vicinity of CARP3 in the bloodstream stage of Trypanosoma brucei.
HostingRepositoryPRIDE
AnnounceDate2022-08-17
AnnouncementXMLSubmission_2022-08-17_01:21:28.459.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDupuy Jean-William
SpeciesList scientific name: Trypanosoma brucei; NCBI TaxID: 5691;
ModificationListbiotinylated residue; acetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-12 23:47:26ID requested
12022-08-17 01:21:28announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: cAMP response protein, CARP3, adenylate cyclase, cyclase-interacting protein, flagellar member 8, FLAM8
Contact List
Michael Boshart
contact affiliationBiocenter, Faculty of Biology, Genetics, Ludwig-Maximilians-University Munich (LMU), 82152 Martinsried, Germany
contact emailboshart@lrz.uni-muenchen.de
lab head
Dupuy Jean-William
contact affiliationPlateforme Proteome Bordeaux
contact emailjean-william.dupuy@u-bordeaux.fr
dataset submitter
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Dataset FTP location
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PRIDE project URI
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