PXD025274

PXD025274 is an original dataset announced via ProteomeXchange.

Title	Time-course proteomic analysis of spontaneously differentiating human embryonic stem cells (hESCs)
Description	Mass spectrometry analysis was carried out to investigate the protein expression landscape of RNA-binding proteins (RBPs) during a time-course of spontaneously differentiating human embryonic stem cells (hESCs). Mass spectrometry was performed on whole-cell extracts of differentiating TE03 (I3) hESCs at four time-points (days 0, 23, 39, and 54), each with two biological replicates.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:45:32.676.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shlomi Dvir
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-08 08:26:24	ID requested
1	2023-05-04 19:16:14	announced
⏵ 2	2023-11-14 08:45:34	announced	2023-11-14: Updated project metadata.

Dvir S, Argoetti A, Lesnik C, Roytblat M, Shriki K, Amit M, Hashimshony T, Mandel-Gutfreund Y, Uncovering the RNA-binding protein landscape in the pluripotency network of human embryonic stem cells. Cell Rep, 35(9):109198(2021) [pubmed]

submitter keyword: early differentiation, spontaneously differentiating, shotgun proteomics, hESCs,mass spectrometry, RBPs, RNA-binding proteins, human embryonic stem cells

Yael Mandel-Gutfreund
contact affiliation	1. Faculty of Biology, Technion - Israel Institute of Technology, Haifa 320003, Israel 2. Computer Science Department, Technion - Israel Institute of Technology, Haifa 320003, Israel
contact email	yaelmg@technion.ac.il
lab head
Shlomi Dvir
contact affiliation	Faculty of Biology, Technion - Israel Institute of Technology, Haifa 320003, Israel
contact email	shlomidvir1@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD025274

PRIDE project URI

• PRIDE
  1. PXD025274
     1. Label: PRIDE project
     2. Name: Time-course proteomic analysis of spontaneously differentiating human embryonic stem cells (hESCs)