PXD025269

PXD025269 is an original dataset announced via ProteomeXchange.

Title	Proteomics of Substance Use Disorder in the Dorsolateral Prefrontal Cortex
Description	Ex vivo large-scale proteomic analysis using LC-MS/MS in postmortem brains of patients with substance use disorder and controls. Brain tissue was collected postmortem after consent from the next of kin. As part of the clinical information, medical records were obtained and a detailed psychological autopsy was performed on all participants by interviewing the next-of-kin. Information regarding the psychiatric clinical phenotypes (evidence of depression, mania, and psychosis) stressful life events, age of drug use onset, types of drugs used, smoking and drinking history, and any co-morbidities, was obtained. A diagnosis of substance use disorder was confirmed based on the psychological autopsy, detailed medical records, and review of all relevant case information by three psychiatrists at a consensus meeting. The cause of death was obtained from the medical examiner’s report and toxicological findings after death.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_00:50:21.111.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Consuelo Walss-Bass
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-08 07:46:35	ID requested
⏵ 1	2022-02-17 00:50:21	announced

Tondo LP, Viola TW, Fries GR, Kluwe-Schiavon B, Rothmann LM, Cupertino R, Ferreira P, Franco AR, Lane SD, Stertz L, Zhao Z, Hu R, Meyer T, Schmitz JM, Walss-Bass C, Grassi-Oliveira R, White matter deficits in cocaine use disorder: convergent evidence from in vivo diffusion tensor imaging and ex vivo proteomic analysis. Transl Psychiatry, 11(1):252(2021) [pubmed]

submitter keyword: Human, Brain, BA9

Consuelo Walss-Bass
contact affiliation	Faillace Department of Psychiatry and Behavioral Sciences University of Texas Health Science Center at Houston
contact email	consuelo.walssbass@uth.tmc.edu
lab head
Consuelo Walss-Bass
contact affiliation	University of Texas Health Science Center at Houston
contact email	consuelo.walssbass@uth.tmc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD025269

PRIDE project URI

• PRIDE
  1. PXD025269
     1. Label: PRIDE project
     2. Name: Proteomics of Substance Use Disorder in the Dorsolateral Prefrontal Cortex