PXD025269 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomics of Substance Use Disorder in the Dorsolateral Prefrontal Cortex |
Description | Ex vivo large-scale proteomic analysis using LC-MS/MS in postmortem brains of patients with substance use disorder and controls. Brain tissue was collected postmortem after consent from the next of kin. As part of the clinical information, medical records were obtained and a detailed psychological autopsy was performed on all participants by interviewing the next-of-kin. Information regarding the psychiatric clinical phenotypes (evidence of depression, mania, and psychosis) stressful life events, age of drug use onset, types of drugs used, smoking and drinking history, and any co-morbidities, was obtained. A diagnosis of substance use disorder was confirmed based on the psychological autopsy, detailed medical records, and review of all relevant case information by three psychiatrists at a consensus meeting. The cause of death was obtained from the medical examiner’s report and toxicological findings after death. |
HostingRepository | PRIDE |
AnnounceDate | 2022-02-17 |
AnnouncementXML | Submission_2022-02-17_00:50:21.111.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Consuelo Walss-Bass |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Elite |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-04-08 07:46:35 | ID requested | |
⏵ 1 | 2022-02-17 00:50:21 | announced | |
Publication List
Tondo LP, Viola TW, Fries GR, Kluwe-Schiavon B, Rothmann LM, Cupertino R, Ferreira P, Franco AR, Lane SD, Stertz L, Zhao Z, Hu R, Meyer T, Schmitz JM, Walss-Bass C, Grassi-Oliveira R, White matter deficits in cocaine use disorder: convergent evidence from in vivo diffusion tensor imaging and ex vivo proteomic analysis. Transl Psychiatry, 11(1):252(2021) [pubmed] |
Keyword List
submitter keyword: Human, Brain, BA9 |
Contact List
Consuelo Walss-Bass |
contact affiliation | Faillace Department of Psychiatry and Behavioral Sciences University of Texas Health Science Center at Houston |
contact email | consuelo.walssbass@uth.tmc.edu |
lab head | |
Consuelo Walss-Bass |
contact affiliation | University of Texas Health Science Center at Houston |
contact email | consuelo.walssbass@uth.tmc.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD025269 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD025269
- Label: PRIDE project
- Name: Proteomics of Substance Use Disorder in the Dorsolateral Prefrontal Cortex