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PXD025269

PXD025269 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics of Substance Use Disorder in the Dorsolateral Prefrontal Cortex
DescriptionEx vivo large-scale proteomic analysis using LC-MS/MS in postmortem brains of patients with substance use disorder and controls. Brain tissue was collected postmortem after consent from the next of kin. As part of the clinical information, medical records were obtained and a detailed psychological autopsy was performed on all participants by interviewing the next-of-kin. Information regarding the psychiatric clinical phenotypes (evidence of depression, mania, and psychosis) stressful life events, age of drug use onset, types of drugs used, smoking and drinking history, and any co-morbidities, was obtained. A diagnosis of substance use disorder was confirmed based on the psychological autopsy, detailed medical records, and review of all relevant case information by three psychiatrists at a consensus meeting. The cause of death was obtained from the medical examiner’s report and toxicological findings after death.
HostingRepositoryPRIDE
AnnounceDate2022-02-17
AnnouncementXMLSubmission_2022-02-17_00:50:21.111.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterConsuelo Walss-Bass
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-08 07:46:35ID requested
12022-02-17 00:50:21announced
Publication List
Tondo LP, Viola TW, Fries GR, Kluwe-Schiavon B, Rothmann LM, Cupertino R, Ferreira P, Franco AR, Lane SD, Stertz L, Zhao Z, Hu R, Meyer T, Schmitz JM, Walss-Bass C, Grassi-Oliveira R, White matter deficits in cocaine use disorder: convergent evidence from in vivo diffusion tensor imaging and ex vivo proteomic analysis. Transl Psychiatry, 11(1):252(2021) [pubmed]
Keyword List
submitter keyword: Human, Brain, BA9
Contact List
Consuelo Walss-Bass
contact affiliationFaillace Department of Psychiatry and Behavioral Sciences University of Texas Health Science Center at Houston
contact emailconsuelo.walssbass@uth.tmc.edu
lab head
Consuelo Walss-Bass
contact affiliationUniversity of Texas Health Science Center at Houston
contact emailconsuelo.walssbass@uth.tmc.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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