PXD025261

PXD025261 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	27-plex Tandem Mass Tag Mass Spectrometry for Profiling Brain Proteome in Alzheimer's Disease
Description	Systematically optimized the protocol for the newly developed 16-plex TMT Reported a novel 27-plex method to enhance the multiplexity for large-scale proteomic profiling, by combining two sets of distinct isobaric tags (11-plex and 16-plex TMT) based on their disparate mass shifts on modified peptides.
HostingRepository	PRIDE
AnnounceDate	2021-04-09
AnnouncementXML	Submission_2021-04-08_22:54:51.993.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhen Wang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-08 05:57:48	ID requested
⏵ 1	2021-04-08 22:54:52	announced

Publication List

Wang Z, Yu K, Tan H, Wu Z, Cho JH, Han X, Sun H, Beach TG, Peng J, 27-Plex Tandem Mass Tag Mass Spectrometry for Profiling Brain Proteome in Alzheimer's Disease. Anal Chem, 92(10):7162-7170(2020) [pubmed]

Wang Z, Yu K, Tan H, Wu Z, Cho JH, Han X, Sun H, Beach TG, Peng J, 27-Plex Tandem Mass Tag Mass Spectrometry for Profiling Brain Proteome in Alzheimer's Disease. Anal Chem, 92(10):7162-7170(2020) [pubmed]

Keyword List

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP)
submitter keyword: TMT
mass spectrometry
proteomics
proteome
Alzheimer’s disease
brain tissue
disease network
Aβ

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP)

submitter keyword: TMT

mass spectrometry

proteomics

proteome

Alzheimer’s disease

brain tissue

disease network

Aβ

Contact List

Junmin Peng
contact affiliation	Structure Biology Department St Jude Children’s Research Hospital
contact email	junmin.peng@stjude.org
lab head
Zhen Wang
contact affiliation	St.Jude Children's Research Hospital
contact email	Zhen.Wang@STJUDE.ORG
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD025261
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD025261

PRIDE project URI

Repository Record List

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