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PXD025247

PXD025247 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleLarge-scale plasma peptidomic profiling reveals a novel, non-toxic, Crassostrea hongkongensis-derived antimicrobial peptide against foodborne pathogens
DescriptionOyster plasma contains various soluble factors secreted by hemocytes and other cells, which were separated from the haemolymph and collected for antibacterial activity as-says. Plasma was collected after V. parahaemolyticus injection, with PBS injection being set as a control. Plasma of the V. parahaemolyticus challenged group was markedly more bac-tericidal than that of the PBS treated control。Peptidomics was herein employed to identify new bioactive peptides with antibacterial activity from plasma based on liquid chromatography and tandem mass spectrometry. To apply large-scale peptidomics to oyster plasma proteins, oyster plasma was extracted from the V. parahaemolyticus challenged group (P4, P5, P6) and PBS treated control (P1, P2, P3).
HostingRepositoryPRIDE
AnnounceDate2021-04-09
AnnouncementXMLSubmission_2021-04-08_22:00:33.234.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLiu Kunna
SpeciesList scientific name: Crassostrea hongkongensis; NCBI TaxID: 298176;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-04-07 06:35:02ID requested
12021-04-08 22:00:33announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: oyster
plasma
peptidomics
antimicrobial peptides
cytotoxicity
Contact List
Yang Zhang
contact affiliationCAS Key Laboratory of Tropical Marine Bio-resources and Ecology and Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Science. Guangzhou, China
contact emailyzhang@scsio.ac.cn
lab head
Liu Kunna
contact affiliationSouth China sea institude of Chinese academy of science
contact email18811361078@163.com
dataset submitter
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Dataset FTP location
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