PXD025247

PXD025247 is an original dataset announced via ProteomeXchange.

Title	Large-scale plasma peptidomic profiling reveals a novel, non-toxic, Crassostrea hongkongensis-derived antimicrobial peptide against foodborne pathogens
Description	Oyster plasma contains various soluble factors secreted by hemocytes and other cells, which were separated from the haemolymph and collected for antibacterial activity as-says. Plasma was collected after V. parahaemolyticus injection, with PBS injection being set as a control. Plasma of the V. parahaemolyticus challenged group was markedly more bac-tericidal than that of the PBS treated control。Peptidomics was herein employed to identify new bioactive peptides with antibacterial activity from plasma based on liquid chromatography and tandem mass spectrometry. To apply large-scale peptidomics to oyster plasma proteins, oyster plasma was extracted from the V. parahaemolyticus challenged group (P4, P5, P6) and PBS treated control (P1, P2, P3).
HostingRepository	PRIDE
AnnounceDate	2021-04-09
AnnouncementXML	Submission_2021-04-08_22:00:33.234.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liu Kunna
SpeciesList	scientific name: Crassostrea hongkongensis; NCBI TaxID: 298176;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-07 06:35:02	ID requested
⏵ 1	2021-04-08 22:00:33	announced

Dataset with its publication pending

submitter keyword: oyster

plasma

peptidomics

antimicrobial peptides

cytotoxicity

Yang Zhang
contact affiliation	CAS Key Laboratory of Tropical Marine Bio-resources and Ecology and Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Science. Guangzhou, China
contact email	yzhang@scsio.ac.cn
lab head
Liu Kunna
contact affiliation	South China sea institude of Chinese academy of science
contact email	18811361078@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD025247

PRIDE project URI

• PRIDE
  1. PXD025247
     1. Label: PRIDE project
     2. Name: Large-scale plasma peptidomic profiling reveals a novel, non-toxic, Crassostrea hongkongensis-derived antimicrobial peptide against foodborne pathogens