PXD025176

PXD025176 is an original dataset announced via ProteomeXchange.

Title	EAE Optic Nerves Injected with LPC 18:1 + Isobaric C13-His
Description	EAE mice were injected with LPC 18:1 and Isobaric C13-His at the optic nerve when they exhibited a clinical score of 2. Visual function was assessed via pattern electroretinogram and optic nerves were harvested 12 days post optic nerve injection. Optic nerves were processed for mass spectrometry to identify the integration of C13-His in newly synthesized proteins.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-17_00:15:50.061.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD025176
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Sanjoy Bhattacharya
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	carbamoylated residue; acetylated residue; monohydroxylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-04-06 00:44:56	ID requested
⏵ 1	2022-02-17 00:15:50	announced

Valdivia AO, Bhattacharya SK, Lyso-Lipid-Induced Oligodendrocyte Maturation Underlies Restoration of Optic Nerve Function. eNeuro, 9(1):(2022) [pubmed]

submitter keyword: LPC 18:1, EAE, Multiple Sclerosis, Optic Nerve

Sanjoy Bhattacharya
contact affiliation	University of Miami Bascom Palmer Eye Institute
contact email	sbhattacharya@med.miami.edu
lab head
Sanjoy Bhattacharya
contact affiliation	Bascom Palmer Eye Institute, Department of Ophthalmology, Miller School of Medicine at University of Miami, Miami, FL 33136, USA
contact email	sbhattacharya@med.miami.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD025176

PRIDE project URI

• PRIDE
  1. PXD025176
     1. Label: PRIDE project
     2. Name: EAE Optic Nerves Injected with LPC 18:1 + Isobaric C13-His