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PXD024966

PXD024966 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEAE Optic Nerve Injections with LPC 18:1 (iTRAQ)
DescriptionEAE mice were injected with LPC 18:1 at the optic nerve when they exhibited a clinical score of 2. Visual function was assessed via pattern electroretinogram and optic nerves were harvested 12 days post optic nerve injection. Three different visual recovery pathways were observed: 1) No-injection control (no recovery in visual function), 2) Low recovery visual function, 3) High recovery visual function and 4) No change in visual function.
HostingRepositoryPRIDE
AnnounceDate2022-02-17
AnnouncementXMLSubmission_2022-02-16_23:52:28.617.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD024966
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterSanjoy Bhattacharya
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiTRAQ8plex-116 reporter+balance reagent acylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-03-23 23:37:26ID requested
12022-02-16 23:52:29announced
Publication List
Valdivia AO, Bhattacharya SK, Lyso-Lipid-Induced Oligodendrocyte Maturation Underlies Restoration of Optic Nerve Function. eNeuro, 9(1):(2022) [pubmed]
Keyword List
submitter keyword: EAE, LPC 18:1, Multiple Sclerosis, iTRAQ
Contact List
Sanjoy Bhattacharya
contact affiliationUniversity of Miami Bascom Palmer Eye Institute
contact emailsbhattacharya@med.miami.edu
lab head
Sanjoy Bhattacharya
contact affiliationBascom Palmer Eye Institute, Department of Ophthalmology, Miller School of Medicine at University of Miami, Miami, FL 33136, USA
contact emailsbhattacharya@med.miami.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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