PXD024961
PXD024961 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Deficiency in Sirtuin3 rewires mitochondrial metabolism and increases maximum lifespan under caloric restriction - Mitochondrial Acetylation Stoichiometry |
Description | Quantification of acetylation stoichiometry from mitochondrial enriched proteins from mouse livers. Conditions compared include genotype, diet, and age; i.e. Sirt3 KO vs Sirt3 WT, caloric restricted (CR) diet vs control diet (CD), and 5 months old vs 25 months old. |
HostingRepository | MassIVE |
AnnounceDate | 2024-01-26 |
AnnouncementXML | Submission_2024-01-26_15:15:59.070.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Alexis Lawton |
SpeciesList | scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; |
ModificationList | Acetyl; Acetyl:2H(3); Oxidation; Carbamidomethyl |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-03-23 09:01:30 | ID requested | |
⏵ 1 | 2024-01-26 15:15:59 | announced |
Publication List
Dhillon RS, Qin YA, van Ginkel PR, Fu VX, Vann JM, Lawton AJ, Green CL, Manchado-Gobatto FB, Gobatto CA, Lamming DW, Prolla TA, Denu JM, SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction. Aging Cell, 21(12):e13721(2022) [pubmed] |
Keyword List
submitter keyword: Acetylation, Stoichiometry, Mitochondria, Metabolism, Sirtuins, Sirt3, Aging, Caloric Restriction |
Contact List
John Denu | |
---|---|
contact affiliation | University of Wisconsin - Madison |
contact email | john.denu@wisc.edu |
lab head | |
Alexis Lawton | |
contact affiliation | University of Wisconsin - Madison |
contact email | alawton2@wisc.edu |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000087085/ |