PXD024947

PXD024947 is an original dataset announced via ProteomeXchange.

Title	Comparative proteomic profiling: cellular metabolisms are mainly affected in Senecavirus A-inoculated cells at an early stage of infection
Description	Senecavirus A (SVA) belongs to the genus Senecavirus in the family Picornaviridae. It is increasingly used for proteomic research that tandem mass tag-labeled liquid chromatography-tandem mass spectrometry is combined with the parallel reaction monitoring technique. In this study, this combined method was used to uncover separately proteomic profiles of SVA- and non-infected BSR-T7/5 cells. Further, both proteomic profiles were compared with each other. The proteomic profiling showed that a total of 361 differentially expressed proteins were identified, out of which, 305 and 56 were upregulated and downregulated in SVA-infected cells at 12 h post-inoculation, respectively. GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) enrichment analyses showed that cellular metabolisms were mainly affected in SVA-inoculated cells at an early stage of infection.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-16_23:51:23.734.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Guolin Li
SpeciesList	scientific name: Cricetulus griseus; NCBI TaxID: 10029;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-23 03:42:00	ID requested
⏵ 1	2022-02-16 23:51:24	announced

Liu F, Ni B, Wei R, A-Inoculated Cells at an Early Stage of Infection. Viruses, 13(6):(2021) [pubmed]

submitter keyword: Senecavirus A, Proteomics, Differentially expressed protein, Enrichment analysis, Metabolism, Pathway.

Fuxiao Liu
contact affiliation	College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, 266109, China
contact email	laudawn@126.com
lab head
Guolin Li
contact affiliation	Hunan Normal University
contact email	hnsdlgl@hunnu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD024947

PRIDE project URI

• PRIDE
  1. PXD024947
     1. Label: PRIDE project
     2. Name: Comparative proteomic profiling: cellular metabolisms are mainly affected in Senecavirus A-inoculated cells at an early stage of infection