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PXD024870

PXD024870 is an original dataset announced via ProteomeXchange.

Dataset Summary
Titlemouse brain prion protein interactome
DescriptionIn vertebrates, the prion protein (PrP, gene name Prnp) is expressed in diverse cell types and tissues, especially in the brain. In the adult brain, PrP contributes to homeostasis. Here, proteins expressed in the adult mouse brain which coimmunoprecipitated with PrP via the Fab antibody D18 were identified by comparison to PrP-specific immunoprecipitates from Prnp knockout brain.
HostingRepositoryPRIDE
AnnounceDate2021-11-02
AnnouncementXMLSubmission_2021-11-02_04:17:42.508.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDeclan Williams
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListS-pyridylethyl-L-cysteine; phosphorylated residue; monohydroxylated residue; deamidated residue
InstrumentOrbitrap Fusion ETD
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-03-19 03:50:52ID requested
12021-11-02 04:17:42announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: brain, neuron, immunoprecipitation, interactome, orbitrap
Contact List
Gerold Schmitt-Ulms
contact affiliationTanz Centre for Research in Neurodegenerative Diseases, Faculty of Medicine, University of Toronto
contact emailg.schmittulms@utoronto.ca
lab head
Declan Williams
contact affiliationUniversity of Toronto
contact emailgwillym.williams@utoronto.ca
dataset submitter
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Dataset FTP location
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PRIDE project URI
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