PXD024647

PXD024647 is an original dataset announced via ProteomeXchange.

Title	proteomics of small extracellular vesicles (sEVs) from adipose tissue derived mesenchymal stem cells (AD-MSCs) stimulated with or without IFN-γ
Description	Mesenchymal stromal cells (MSCs) are used for ameliorating liver fibrosis and aiding liver regeneration after cirrhosis; Here, we analyzed the therapeutic potential of small extracellular vesicles (sEVs) derived from interferon-γ (IFN-γ) pre-conditioned MSCs (γ-sEVs). to anlyze the proteins in sEVs, proteomics of small extracellular vesicles (sEVs) from adipose tissue derived mesenchymal stem cells (AD-MSCs) stimulated with or without IFN-γ were performed.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-16_16:52:16.835.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD024647
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Atsunori Tsuchiya
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-10 06:42:28	ID requested
⏵ 1	2022-02-16 16:52:17	announced

Takeuchi S, Tsuchiya A, Iwasawa T, Nojiri S, Watanabe T, Ogawa M, Yoshida T, Fujiki K, Koui Y, Kido T, Yoshioka Y, Fujita M, Kikuta J, Itoh T, Takamura M, Shirahige K, Ishii M, Ochiya T, Miyajima A, Terai S, pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis. NPJ Regen Med, 6(1):19(2021) [pubmed]

submitter keyword: small extracellular vesicle, mesenchymal stem cells

Shuji Terai
contact affiliation	Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University
contact email	terai@med.niigata-u.ac.jp
lab head
Atsunori Tsuchiya
contact affiliation	Niigata University
contact email	atsunori@med.niigata-u.ac.jp
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD024647

PRIDE project URI

• PRIDE
  1. PXD024647
     1. Label: PRIDE project
     2. Name: proteomics of small extracellular vesicles (sEVs) from adipose tissue derived mesenchymal stem cells (AD-MSCs) stimulated with or without IFN-γ