PXD024628

PXD024628 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Control and Ikbkap-knockout MEFs LC-MSMS
Description	Mouse Ikbkap gene encodes IKAP/Elp1- one of the core subunits of Elongator- and has been implicated in translational regulation. However, a role for IKAP in genome maintenance remains unclear. In this study, we analyze proteins from control and Ikbkap depletion mouse embryonic fibroblasts (MEF) using MS. Using MS-based proteomics, we show that several proteins involved in cancer and DNA damage response were found to be differentially expressed upon Ikbkap depletion.
HostingRepository	PRIDE
AnnounceDate	2022-02-17
AnnouncementXML	Submission_2022-02-16_16:44:26.377.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	FU-JUNG LIN
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-10 02:19:43	ID requested
⏵ 1	2022-02-16 16:44:27	announced

Publication List

Chen WT, Tseng HY, Jiang CL, Lee CY, Chi P, Chen LY, Lo KY, Wang IC, Lin FJ, Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation. J Biomed Sci, 28(1):81(2021) [pubmed]

Chen WT, Tseng HY, Jiang CL, Lee CY, Chi P, Chen LY, Lo KY, Wang IC, Lin FJ, Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation. J Biomed Sci, 28(1):81(2021) [pubmed]

Keyword List

submitter keyword: Ikbkap, MEFs, LC-MSMS

submitter keyword: Ikbkap, MEFs, LC-MSMS

Contact List

Fu-Jung Lin
contact affiliation	National Taiwan University
contact email	fujlin@ntu.edu.tw
lab head
FU-JUNG LIN
contact affiliation	National Taiwan University
contact email	fujlin@ntu.edu.tw
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD024628
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD024628

PRIDE project URI

Repository Record List

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