PXD024596

PXD024596 is an original dataset announced via ProteomeXchange.

Title	Dengzhan shengmai brian mitochondrial proteome
Description	To improve our understanding on neuroprotective effect, afford by DZSM on CCH, we constructed two independent quantitative mitochondrial proteome and phospho-proteome experiment for dissecting the therapy of DZSM, data shows that DZSM attenuated CCH by regulating mitochondrial-mediated pathway (mainly TCA cycle and OXPHOS). The differentially expressed mitochondrial proteins identified such as Atp5o, Cox4il and Dlat were related to mitochondrial TCA cycle and OXPHOS, which were further validated by parallel reaction monitoring (PRM) technology.
HostingRepository	iProX
AnnounceDate	2021-03-08
AnnouncementXML	Submission_2021-03-09_00:07:36.821.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hao Zheng
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	phosphorylated residue; TMT6plex reporter fragment
Instrument	Orbitrap Fusion Lumos; TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-09 00:06:43	ID requested
⏵ 1	2021-03-09 00:07:37	announced

Dataset with its publication pending

submitter keyword: Dengzhan shengmai brian mitochondrial proteome

Jinlan Zhang
contact affiliation	Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College
contact email	zhangjl@imm.ac.cn
lab head
Hao Zheng
contact affiliation	institute of materia medica, Chinese academy of medical science
contact email	595113331@qq.com
dataset submitter

iProX dataset URI