PXD024509

PXD024509 is an original dataset announced via ProteomeXchange.

Title	Metaproteomics reveals functional changes in the fecal microbiota of rats under time-restricted feeding
Description	Diet is a key factor influencing gut microbiota (GM) composition and functions, which in turn affect host health. Among dietary regimens, time-restricted (TR) feeding has been associated to numerous health benefits. To date, little is known about the modulation of GM protein functions by TR feeding. Here, we analyzed the effects of TR feeding on GM protein expression in a rat model through a metaproteomic approach. We observed that TR feeding has a relevant impact on GM functions, especially on several biological activities exerted by members of the genus Lactobacillus, including proteolysis and metabolism of galactose-containing glycans.
HostingRepository	PRIDE
AnnounceDate	2021-10-15
AnnouncementXML	Submission_2021-10-15_07:08:42.545.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Antonio Palomba
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; scientific name: rat gut metagenome; NCBI TaxID: 1436733;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-03 22:21:22	ID requested
⏵ 1	2021-10-15 07:08:42	announced

Dataset with its publication pending

submitter keyword: diet, fasting, galactose metabolism, gut microbiota, Lactobacillus, metaproteomics, mucin degradation, rodent, time-restricted feeding

Daniela Pagnozzi
contact affiliation	Porto Conte Ricerche Srl, Science and Technology Park of Sardinia, Alghero, Italy
contact email	pagnozzi@portocontericerche.it
lab head
Antonio Palomba
contact affiliation	Porto Conte Ricerche
contact email	palomba@portocontericerche.it
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/10/PXD024509

PRIDE project URI

• PRIDE
  1. PXD024509
     1. Label: PRIDE project
     2. Name: Metaproteomics reveals functional changes in the fecal microbiota of rats under time-restricted feeding