PXD024449

PXD024449 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Characterisation of cancer stem cells and the renin-angiotensin system in colon adenocarcinoma
Description	LC-MS/MS Proteomics was performed to determine proteomic differences between colon adenocarcinoma (CA) tissues and patient-matched normal colon tissues, CA-derived primary cell lines and NC-derived primary cells, and between LGCA tissues and cell lines and HGCA tissues and cell lines. Biological processes which may link the renin-angiotensin system and CA were investigated, revealing enrichment of various signalling pathways that may play roles in CA onset and progression directly or via the renin-angiotensin system.
HostingRepository	PRIDE
AnnounceDate	2022-08-12
AnnouncementXML	Submission_2022-08-12_02:31:13.769.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD024449
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Danyl Mclauchlan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-01 10:02:32	ID requested
⏵ 1	2022-08-12 02:31:14	announced

Publication List

Munro MJ, Wickremesekera SK, Tan ST, Peng L, Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates. Clin Proteomics, 19(1):27(2022) [pubmed]

Munro MJ, Wickremesekera SK, Tan ST, Peng L, Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates. Clin Proteomics, 19(1):27(2022) [pubmed]

Keyword List

submitter keyword: CRC, colon adenocarcinoma, primary cell lines, LC-MS/MS

submitter keyword: CRC, colon adenocarcinoma, primary cell lines, LC-MS/MS

Contact List

Lifeng Peng
contact affiliation	School of Biological Sciences, Victoria University of Wellington
contact email	lifeng.peng@vuw.ac.nz
lab head
Danyl Mclauchlan
contact affiliation	Centre for Biodiscovery
contact email	danyl.mclauchlan@vuw.ac.nz
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD024449
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD024449

PRIDE project URI

Repository Record List

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