PXD024412

PXD024412 is an original dataset announced via ProteomeXchange.

Title	KRAS Epitope Identification Immunopeptidomics
Description	Utilizing computational epitope prediction and biochemical assays we predicted and identified high-affinity and/or high-stability KRAS peptides to high prevalence HLA class I molecules. Using single HLA class I allele lines and tumor cell lines in conjunction with MS spectrometry, selected mKRAS epitopes were identified as constituents of the HLA class I ligandome.
HostingRepository	PRIDE
AnnounceDate	2021-05-29
AnnouncementXML	Submission_2021-05-29_05:09:41.734.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD024412
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Beatriz Carreno
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; deamidated residue
Instrument	Q Exactive HF; Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-28 22:44:52	ID requested
⏵ 1	2021-05-29 05:09:42	announced

Dataset with its publication pending

submitter keyword: Epitope, T cells, TCR, Cancer Immunotherapy

Beatriz M. Carreno
contact affiliation	Parker Institute for Cancer Immunotherapy, Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, South Pavilion Tower, Building 421, Rm 8-103 3400 Civic Center Blvd. Philadelphia, PA 19104-5157
contact email	bcarreno@upenn.edu
lab head
Beatriz Carreno
contact affiliation	Univeristy of Pennsylvania
contact email	bcarreno@upenn.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/05/PXD024412

PRIDE project URI

• PRIDE
  1. PXD024412
     1. Label: PRIDE project
     2. Name: KRAS Epitope Identification Immunopeptidomics