PXD024408

PXD024408 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Molecular Profiling of Two HPV16+ OPSCC Brain Metastases
Description	We report a detailed characterization of the HPV16 genome in two brain metastases from OPSCC tumors. The use of a target enrichment strategy followed by next generation sequencing (NGS) provided an effective way to identify viral infection in tumor genome, including internal deletions and insertion sites into the host genome. Applying similar strategies to a larger cohort of HPV+ HNSCC brain metastases could help to identify biomarkers that can predict metastasis and/or identify novel therapeutic options.
HostingRepository	MassIVE
AnnounceDate	2021-08-12
AnnouncementXML	Submission_2021-08-12_16:53:19.514.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Brian Searle
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Carbamidomethyl
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-28 20:21:27	ID requested
⏵ 1	2021-08-12 16:53:19	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: HPV16, brain metastases

submitter keyword: HPV16, brain metastases

Contact List

Brian Searle
contact affiliation	Institute for Systems Biology
contact email	bsearle@systemsbiology.org
lab head
Brian Searle
contact affiliation	Institute for Systems Biology
contact email	bsearle@systemsbiology.org
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000086965/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000086965/