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PXD024351

PXD024351 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMorphine-treated Primary Brain Endothelial Cells LC-MS/MS DIA
DescriptionThis project aimed at investigating the impact of morphine exposure on brain endothelial cells via an in vitro monoculture of primary human brain microvascular endothelial cells (HBMECs) and state of the art mass spectrometry-based proteomics, using a data-independent acquisition (DIA) MS-based quantitative approach. HBMECS were exposed to morphine at three different concentrations (1, 10, 100 uM) and for two different time points (24h and 48h) to explore dose- and time-dependent effects.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:51:20.818.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSandrine Reymond
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-02-24 03:03:00ID requested
12022-03-21 01:03:42announced
22023-11-14 08:51:21announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Brain, DIA, Endothelial, Morphine, LC-MS/MS
Contact List
Jean-Charles Sanchez
contact affiliationTranslational Biomarker Group, Department of Medicine, University of Geneva
contact emailJean-Charles.Sanchez@unige.ch
lab head
Sandrine Reymond
contact affiliationUniversity of Geneva
contact emailsandrine.reymond@unige.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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