PXD024233

PXD024233 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Reading ADP-ribosylation signalling using chemical biology and interaction proteomics
Description	In this project, we describe a global, proteome-wide screening for ADP-ribosylation interactome. Our data reveals novel MAR and PAR readers. We identify both cell type-dependent and independent ADPr interactors. In addition, we quantify apparent binding affinities of large number of ADPr readers. We also identify proteins, whose interaction with ADPr modifications is regulated upon DNA damage induction.
HostingRepository	PRIDE
AnnounceDate	2021-11-02
AnnouncementXML	Submission_2021-11-02_04:14:45.165.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pascal Jansen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480; Orbitrap Fusion; Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-18 06:00:25	ID requested
⏵ 1	2021-11-02 04:14:45	announced

Publication List

Kliza KW, Liu Q, Roosenboom LWM, Jansen PWTC, Filippov DV, Vermeulen M, Reading ADP-ribosylation signaling using chemical biology and interaction proteomics. Mol Cell, 81(21):4552-4567.e8(2021) [pubmed]

Kliza KW, Liu Q, Roosenboom LWM, Jansen PWTC, Filippov DV, Vermeulen M, Reading ADP-ribosylation signaling using chemical biology and interaction proteomics. Mol Cell, 81(21):4552-4567.e8(2021) [pubmed]

Keyword List

submitter keyword: ADP-ribosylation, ADPr-binding proteins

submitter keyword: ADP-ribosylation, ADPr-binding proteins

Contact List

Prof. Michiel Vermeulen
contact affiliation	Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, 6525 GA, The Netherlands
contact email	Michiel.Vermeulen@science.ru.nl
lab head
Pascal Jansen
contact affiliation	Radboud University
contact email	p.jansen@science.ru.nl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD024233
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD024233

PRIDE project URI

Repository Record List

[ + ]