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PXD024161

PXD024161 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePeptidomics of pancreas in wild type and neuronatin deficien mice
DescriptionPancreata of wild type and a neuronatin deficient mouse strain were homogenised and the peptidome characterised. Particular attention was paid to the processing of insulin, to assess if neuronatin deficiency causes changes in the processing efficiency of insulin and other bioactive peptides produced in the pancreas
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:29:57.732.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD024161
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterRichard Kay
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListamidated residue; 2-pyrrolidone-5-carboxylic acid (Gln); acetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-02-12 06:07:12ID requested
12021-11-03 02:44:40announced
22024-10-22 05:29:58announced2024-10-22: Updated project metadata.
Publication List
10.6019/PXD024161;
Cimino I, Rimmington D, Tung YCL, Lawler K, Larraufie P, Kay RG, Virtue S, Lam BYH, Fagnocchi L, Ma MKL, Saudek V, Zvetkova I, Vidal-Puig A, Yeo GSH, Farooqi IS, Pospisilik JA, Gribble FM, Reimann F, O'Rahilly S, Coll AP, Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity. Sci Rep, 11(1):17571(2021) [pubmed]
10.1038/s41598-021-96278-8;
Keyword List
submitter keyword: neuronatin, prohormone processing,Peptidomics, Pancreas, insulin
Contact List
Dr Anthony Coll
contact affiliationWellcome - MRC Institute of Metabolic Science, University of Cambridge
contact emailapc36@cam.ac.uk
lab head
Richard Kay
contact affiliationUniversity of Cambridge
contact emailrgk27@medschl.cam.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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