PXD024138

PXD024138 is an original dataset announced via ProteomeXchange.

Title	Proteomic response of Escherichia coli to membrane lytic and iron chelating Amaranthus tricolor defensin
Description	Plant defensins are a broadly distributed family of antimicrobial peptides which have been primarily studied for agriculturally relevant antifungal activity. Recent studies have probed defensins against gram negative bacteria revealing evidence for multiple mechanisms of action including membrane lysis and ribosomal inhibition. In this study, a γ-core motif synthetic analog ( Atr-DEF2(G39-C55) ) of Amaranthus tricolor DEF2 (Atr-DEF2) is used to probe plant defensin antibacterial mechanism of action via proteomics.
HostingRepository	PRIDE
AnnounceDate	2021-04-14
AnnouncementXML	Submission_2021-04-13_22:55:30.973.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD024138
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Leslie Hicks
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-11 07:59:21	ID requested
⏵ 1	2021-04-13 22:55:31	announced

Moyer TB, Purvis AL, Wommack AJ, Hicks LM, Proteomic response of Escherichia coli to a membrane lytic and iron chelating truncated Amaranthus tricolor defensin. BMC Microbiol, 21(1):110(2021) [pubmed]

submitter keyword: defensins, Amaranthus tricolor, membrane lysis, iron chelation, iron reduction, Escherichia coli

Leslie M. Hicks
contact affiliation	University of North Carolina at Chapel Hill, Department of Chemistry
contact email	lmhicks@unc.edu
lab head
Leslie Hicks
contact affiliation	University of North Carolina at Chapel Hill
contact email	lmhicks@unc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD024138

PRIDE project URI

• PRIDE
  1. PXD024138
     1. Label: PRIDE project
     2. Name: Proteomic response of Escherichia coli to membrane lytic and iron chelating Amaranthus tricolor defensin