PXD024132

PXD024132 is an original dataset announced via ProteomeXchange.

Title	Long-term changes following pre-conditioned circulating angiogenic cells therapy in critical limb ischemia
Description	Critical limb ischemia (CLI), results from a severe blockade of the arterial vessels, is usually correlated to atherosclerosis. Circulating angiogenic cells (CACs) constitute a good alternative as CLI cell therapy due to their vascular regenerative potential, although the mechanisms of action of these cells as well as their response to pathological conditions remains unclear. Previously, we have shown that the incubation ex vivo of CACs with factors secreted by atheroma plaques promotes the activation and mobilization of these cells. Herein, we have evaluated the long-term effect of CACs administration in CLI mice, whether pre-stimulated or not with atherosclerotic factors.
HostingRepository	PRIDE
AnnounceDate	2022-02-16
AnnouncementXML	Submission_2022-02-16_15:35:30.802.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lucía Beltrán-Camacho
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-11 03:34:47	ID requested
⏵ 1	2022-02-16 15:35:31	announced

Beltr, á, n-Camacho L, Jim, é, nez-Palomares M, Sanchez-Gomar I, Rosal-Vela A, Rojas-Torres M, Eslava-Alcon S, Alonso-Pi, ñ, ero JA, Gonz, á, lez-Rovira A, Extremera-Garc, í, a MJ, Conejero R, Doiz E, Rodriguez-Pi, ñ, ero M, Larsen MR, Duran-Ruiz MC, Long Term Response to Circulating Angiogenic Cells, Unstimulated or Atherosclerotic Pre-Conditioned, in Critical Limb Ischemic Mice. Biomedicines, 9(9):(2021) [pubmed]

submitter keyword: Circulating angiogenic cells, critical limb ischemia, atherosclerotic secretome, neovascularization, immune cells

Mª Carmen Duran-Ruiz
contact affiliation	University of Cadiz and Institute of reserach and innovation in biomedical sciences of Cadiz
contact email	maricarmen.duran@gm.uca.es
lab head
Lucía Beltrán-Camacho
contact affiliation	University of Cádiz Institute of Biomediccal Research of Cádiz
contact email	belcamlucia@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD024132

PRIDE project URI

• PRIDE
  1. PXD024132
     1. Label: PRIDE project
     2. Name: Long-term changes following pre-conditioned circulating angiogenic cells therapy in critical limb ischemia