PXD024039

PXD024039 is an original dataset announced via ProteomeXchange.

Title	Effect of ATP2 deletion on protein expression in Candida albicans
Description	To investigate the effect of ATP2 knockdown on the protein expression of Candida albicans, we performed proteomic assays for atp2Δ/Δ and wild type strains. A total of 4000.0 proteins were identified in this study, of which 3652.0 proteins contained quantitative information. If a 1.5-fold differential expression change threshold and a statistical test t-test p-value < 0.05 were used as the significance threshold, then among the quantified proteins, we found that 112 proteins were up-regulated and 268 proteins were down-regulated in atp2Δ/Δ cells. Based on the above data, we performed systematic bioinformatics analysis (protein functional annotation) of all identified proteins, and performed functional classification, functional enrichment and functional enrichment-based clustering analysis of all differentially expressed proteins.
HostingRepository	PRIDE
AnnounceDate	2021-09-10
AnnouncementXML	Submission_2021-09-10_00:19:05.621.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yishan Zhang
SpeciesList	scientific name: Candida albicans (Yeast); NCBI TaxID: 5476;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-08 00:09:16	ID requested
⏵ 1	2021-09-10 00:19:06	announced

Zhang Y, Tang C, Zhang Z, Li S, Zhao Y, Weng L, Zhang H, Blocks Its Escape From Macrophage Clearance. Front Cell Infect Microbiol, 11():643121(2021) [pubmed]

submitter keyword: Candida albicans

ATP2 gene

macrophage

Hong Zhang
contact affiliation	Jinan University
contact email	tzhangh@jnu.edu.cn
lab head
Yishan Zhang
contact affiliation	First Affiliated Hospital of Jinan University
contact email	zys@stu2015.jnu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD024039

PRIDE project URI

• PRIDE
  1. PXD024039
     1. Label: PRIDE project
     2. Name: Effect of ATP2 deletion on protein expression in Candida albicans