PXD023938

PXD023938 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of human sepsis monocytes
Description	In this project we performed a comprehensive exploration of monocyte molecular responses in a cohort of patients with septic shock via label-free shotgun proteomics. We enrolled adult (≥18 years old) patients with sepsis from community-acquired infections, diagnosed according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) criteria. Blood samples were obtained within the first 72 hours from the diagnosis of sepsis (sepsis phase) and on de day before ICU discharge (recovery phase). The Control group consisted of age matched healthy volunteers. We excluded subjects with AIDS, advanced cancer, hematological diseases, and pregnancy.
HostingRepository	PRIDE
AnnounceDate	2021-09-07
AnnouncementXML	Submission_2021-09-07_04:04:37.787.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Monique Trugilho
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue; deamidated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-02 01:54:48	ID requested
⏵ 1	2021-09-07 04:04:38	announced

de Azambuja Rodrigues PM, Valente RH, Brunoro GVF, Nakaya HTI, Ara, ú, jo-Pereira M, Bozza PT, Bozza FA, Trugilho MRO, Proteomics reveals disturbances in the immune response and energy metabolism of monocytes from patients with septic shock. Sci Rep, 11(1):15149(2021) [pubmed]

submitter keyword: Sepsis, Septic shock, infection, human, monocyte, blood

Monique Trugilho
contact affiliation	Center for Technological Development in Health (CDTS) - FIOCRUZ, Brazil.
contact email	mrotrugilho@hotmail.com
lab head
Monique Trugilho
contact affiliation	Center for Technological Development in Health (CDTS/FIOCRUZ)
contact email	mrotrugilho@hotmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD023938

PRIDE project URI

• PRIDE
  1. PXD023938
     1. Label: PRIDE project
     2. Name: Proteomic analysis of human sepsis monocytes