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PXD023930

PXD023930 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleN-terminal peptides of LAG-3 (WT, V20A, and L14Q/V20A) were quantified by PRM
DescriptionThe abundance of N-terminal fragments starting from V21 (pV21–W33), S22 (pS22–W33), S23 (pS23–W33), and G24 (pG24–W33) along with three control peptides (Ctrl1, pH81–Y95; Ctrl2, pR106–L118; Ctrl3, pH113–L123) were measured by parallel reaction monitoring (PRM), an MS/MS-based targeted quantification method using high-resolution MS. Targeted MS/MS scans were acquired by a time-scheduled inclusion list, and time alignment and relative quantification of the transitions of three biological replicates were performed with PinPoint version 1.4 (Thermo Fisher Scientific).
HostingRepositoryjPOST
AnnounceDate2022-04-11
AnnouncementXMLSubmission_2022-09-18_03:29:12.498.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHidetaka Kosako
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListS-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide
Instrumentinstrument
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-02-02 01:33:44ID requested
12022-04-10 08:00:08announced
22022-04-19 23:00:39announced2022-04-20: Updated PubMed.
32022-09-18 03:29:13announced2022-09-18: Updated FTP location.
Publication List
Maruhashi T, Sugiura D, Okazaki IM, Shimizu K, Maeda TK, Ikubo J, Yoshikawa H, Maenaka K, Ishimaru N, Kosako H, Takemoto T, Okazaki T, cell function and suppresses autoimmunity and anti-cancer immunity. Immunity, 55(5):912-924.e8(2022) [pubmed]
Keyword List
submitter keyword: LAG-3, N-terminal peptides, PRM
Contact List
Hidetaka Kosako
lab head
Hidetaka Kosako
contact affiliationTokushima University
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001077/