PXD023890

PXD023890 is an original dataset announced via ProteomeXchange.

Title	Matrix-Bound Growth Factors are Released upon Cartilage Compression by an Aggrecan-Dependent Sodium Flux that is Lost in Osteoarthritis (Proteomics)
Description	Articular cartilage exhibits regional and depth-dependent biomechanical differences, which influence the transduction of load to chondrocytes and throughout the tissue matrix. One such mechanism is the biophysical release of proteins from the matrix. This study conducted proteomic analysis of rested porcine articular cartilage to assess regional protein abundance throughout distinct depths of porcine knee articular cartilage.
HostingRepository	PRIDE
AnnounceDate	2021-07-23
AnnouncementXML	Submission_2021-07-23_02:48:45.928.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Patrik Onnerfjord
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-29 07:42:11	ID requested
⏵ 1	2021-07-23 02:48:46	announced

Dataset with its publication pending

submitter keyword: porcine, cartilage, growth factors

Patrik Onnerfjord
contact affiliation	BMC-C12, Rheumatology and Molecular Skeletal Biology Department of Clinical Sciences Lund, Lund University SE-22184 Lund, Sweden
contact email	patrik.onnerfjord@med.lu.se
lab head
Patrik Onnerfjord
contact affiliation	Lund University
contact email	patrik.onnerfjord@med.lu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD023890

PRIDE project URI

• PRIDE
  1. PXD023890
     1. Label: PRIDE project
     2. Name: Matrix-Bound Growth Factors are Released upon Cartilage Compression by an Aggrecan-Dependent Sodium Flux that is Lost in Osteoarthritis (Proteomics)