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PXD023875

PXD023875 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman-Soybean Allergies: Elucidation of the Seed Proteome & Comprehensive PPI Prediction
DescriptionIn this work, a total of eight proteins have been identified (six specific to the human proteome and two specific to the soybean proteome) that are supported by literature to be involved in human health, specifically related to immunological and neurological pathways. Our approach involved the use of the Protein-protein Interaction Prediction Engine (PIPE4) algorithm which was specifically developed for complex inter- and cross-species prediction schemas to generate the comprehensive interactome between H. sapiens and G. max. A literature-curated list of human proteins known to be associated with the Human Allergy Response and a second literature-curated list of soybean proteins known to be associated with Soybean Allergens were used to identify candidate proteins whose interactions may be consequential to human health. This study, beyond generating the most comprehensive human-soybean interactome to date, elucidated a soybean seed interactome and identified several proteins putatively consequential to human health.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:44:22.580.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSadhna Phanse
SpeciesList scientific name: Glycine max; NCBI TaxID: 3847;
ModificationListmono N-acetylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-01-29 01:29:25ID requested
12023-03-22 09:14:21announced
22023-11-14 08:44:24announced2023-11-14: Updated project metadata.
Publication List
Dick K, Pattang A, Hooker J, Nissan N, Sadowski M, Barnes B, Tan LH, Burnside D, Phanse S, Aoki H, Babu M, Dehne F, Golshani A, Cober ER, Green JR, Samanfar B, Human-Soybean Allergies: Elucidation of the Seed Proteome and Comprehensive Protein-Protein Interaction Prediction. J Proteome Res, 20(11):4925-4947(2021) [pubmed]
Keyword List
submitter keyword: Human, PPI, PIPE, Allergy, Seed protein, Glycine max, MS/MS spectra,Soybean, Computational Biology
Contact List
Bahram Samanfar
contact affiliationAgriculture and Agri-Food Canada, Ottawa Research and Development Centre
contact emailbahram.samanfar@canada.ca
lab head
Sadhna Phanse
contact affiliationUniversity of Toronto; University of Regina
contact emailsrphanse@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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