PXD023758

PXD023758 is an original dataset announced via ProteomeXchange.

Title	Human TRPV4 LC-MS protein interactor screen
Description	TRPV4 is a cell surface-expressed calcium-permeable cation channel that mediates cell-specific effects on cellular morphology and function. Dominant missense mutations of TRPV4 cause various forms of inherited neuropathy, but the pathogenic mechanisms are unknown. Using an unbiased screen, we sought to identify novel TRPV4 interactors that may be relevant to disease pathogenesis.
HostingRepository	PRIDE
AnnounceDate	2021-01-29
AnnouncementXML	Submission_2021-01-29_04:45:13.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD023758
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Brett McCray
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-22 06:51:37	ID requested
⏵ 1	2021-01-29 04:45:14	announced

Dataset with its publication pending

submitter keyword: TRPV4, HEK-293T, CMT2C

Charlotte Jane Sumner
contact affiliation	Department of Neurology, Johns Hopkins School of Medicine
contact email	csumner1@jhmi.edu
lab head
Brett McCray
contact affiliation	Johns Hopkins School of Medicine
contact email	bmccray3@jhmi.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/01/PXD023758

PRIDE project URI

• PRIDE
  1. PXD023758
     1. Label: PRIDE project
     2. Name: Human TRPV4 LC-MS protein interactor screen