PXD023663

PXD023663 is an original dataset announced via ProteomeXchange.

Title	Investigation of region specific lipid alterations in symptomatic atherosclerotic plaques using mass spectrometry imaging
Description	Atherosclerotic plaques are composed by different cell populations that interact one with each other in a complex and heterogeneous environment. Here we report a MALDI mass spectrometry imaging investigation of the lipid profile of specific plaque regions, to discriminate between symptomatic and asymptomatic atheromas. Regions were defined by histologic staining and immunofluorescence of consecutive tissue sections.
HostingRepository	PRIDE
AnnounceDate	2021-09-10
AnnouncementXML	Submission_2021-09-10_00:11:36.126.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Francesco Greco
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-19 02:14:22	ID requested
⏵ 1	2021-09-10 00:11:36	announced

Greco F, Quercioli L, Pucci A, Rocchiccioli S, Ferrari M, Recchia FA, McDonnell LA, Mass Spectrometry Imaging as a Tool to Investigate Region Specific Lipid Alterations in Symptomatic Human Carotid Atherosclerotic Plaques. Metabolites, 11(4):(2021) [pubmed]

submitter keyword: MALDI MSI, atherosclerosis, plaque vulnerability, lipids, macrophages, VSMCs

Liam Andrew McDonnell
contact affiliation	Fondazione Pisana per la Scienza ONLUS, 56017 San Giuliano Terme (PI), Italy
contact email	liam@fpscience.it
lab head
Francesco Greco
contact affiliation	Scuola Superiore Sant'Anna, Pisa
contact email	fr.greco@santannapisa.it
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD023663

PRIDE project URI

• PRIDE
  1. PXD023663
     1. Label: PRIDE project
     2. Name: Investigation of region specific lipid alterations in symptomatic atherosclerotic plaques using mass spectrometry imaging