PXD023656

PXD023656 is an original dataset announced via ProteomeXchange.

Title	3 days injured in vivo ASCs proteome
Description	Muscle Stem Cells or satellite cells (SCs) are required for muscle regeneration. In resting muscles, SCs are kept in quiescence. After injury, SCs undergo rapid activation, proliferation and differentiation to repair damaged muscles. The transcriptome alteration during SC activation is well characterized. While transcriptome is not exactly represent proteome because of post-transcriptional regulations such as miRNA induced gene silencing. However, little is known about SC proteome. We obtained in vivo activated SCs (ASCs) from 3 days post injured muscles for high resolution mass spectrometry Bruker timsTOF Pro. Compared with QSC proteome,, we identified the pathways that are differentially expressed between them.
HostingRepository	PRIDE
AnnounceDate	2021-11-04
AnnouncementXML	Submission_2021-11-04_00:32:55.924.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD023656
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Tom Cheung
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-18 02:25:29	ID requested
⏵ 1	2021-11-04 00:32:56	announced

Dataset with its publication pending

submitter keyword: Mouse Activated Muscle Stem Cells, timsTOF

Tom H.Cheung
contact affiliation	Hong Kong University of Science and Technology
contact email	tcheung@ust.hk
lab head
Tom Cheung
contact affiliation	Hong Kong University of Science and Technology
contact email	tcheung@ust.hk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD023656
     1. Label: PRIDE project
     2. Name: 3 days injured in vivo ASCs proteome