PXD023572

PXD023572 is an original dataset announced via ProteomeXchange.

Title	Rituximab and obinutuzumab differentially hijack the B-cell receptor and NOTCH1 signaling pathways.
Description	An LC-MS/MS based phosphoproteomics study that characterizes the signaling processes downstream of the B-cell receptor and how they are differentially regulated following treatment with anti-CD20 monoclonal antibodies in B-cell lymphoma.
HostingRepository	PRIDE
AnnounceDate	2021-09-10
AnnouncementXML	Submission_2021-09-09_16:03:00.277.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD023572
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Arran Dokal
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-13 08:35:03	ID requested
⏵ 1	2021-09-09 16:03:01	announced

Edelmann J, Dokal AD, Vilventhraraja E, Holzmann K, Britton D, Klymenko T, D, ö, hner H, Cragg M, Braun A, Cutillas P, Gribben JG, Rituximab and obinutuzumab differentially hijack the B cell receptor and NOTCH1 signaling pathways. iScience, 24(2):102089(2021) [pubmed]

submitter keyword: CD20, Phosphoproteomics,

Pedro Cutillas
contact affiliation	Barts Cancer Institute, Queen Mary University of London
contact email	p.cutillas@qmul.ac.uk
lab head
Arran Dokal
contact affiliation	Barts Cancer Institute, Queen Mary University of London
contact email	a.d.dokal@qmul.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD023572

PRIDE project URI

• PRIDE
  1. PXD023572
     1. Label: PRIDE project
     2. Name: Rituximab and obinutuzumab differentially hijack the B-cell receptor and NOTCH1 signaling pathways.