PXD023511

PXD023511 is an original dataset announced via ProteomeXchange.

Title	ChIRP-MS of the lncRNA SAMMSON in uveal melanoma
Description	Long non-coding RNAs (lncRNAs) can exhibit cell-type or even cancer-type specific expression profiles, making them highly attractive as therapeutic targets. PAN cancer RNA sequencing data revealed sustained expression of the SAMMSON lncRNA in uveal melanoma (UM), the most common primary intraocular malignancy in adults. Currently, there are no effective treatments for UM patients with metastatic disease, resulting in a median survival time of 6-12 months. We aimed to investigate the therapeutic potential of SAMMSON inhibition in UM.
HostingRepository	PRIDE
AnnounceDate	2021-10-04
AnnouncementXML	Submission_2021-10-04_06:32:26.536.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Louis Delhaye
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-11 07:15:44	ID requested
⏵ 1	2021-10-04 06:32:27	announced

Dewaele S, Delhaye L, De Paepe B, de Bony EJ, De Wilde J, Vanderheyden K, Anckaert J, Yigit N, Nuytens J, Vanden Eynde E, Smet J, Verschoore M, Nemati F, Decaudin D, Rodrigues M, Zhao P, Jochemsen A, Leucci E, Vandesompele J, Van Dorpe J, Marine JC, Van Coster R, Eyckerman S, Mestdagh P, The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival. Oncogene, 41(1):15-25(2022) [pubmed]

submitter keyword: ChIRP-MS, lncRNA, SAMMSON

Sven Eyckerman
contact affiliation	VIB-UGent Center for Medical Biotechnology UGent Department of Biomolecular Medicine
contact email	sven.eyckerman@ugent.vib.be
lab head
Louis Delhaye
contact affiliation	VIB-UGent
contact email	louis.delhaye@ugent.vib.be
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/10/PXD023511

PRIDE project URI

• PRIDE
  1. PXD023511
     1. Label: PRIDE project
     2. Name: ChIRP-MS of the lncRNA SAMMSON in uveal melanoma