PXD023477
PXD023477 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome analysis of brain vessels (the anterior cerebral artery and the middle cerebral artery) from 24-month-old candesartan-treated and nontreated Htra1 KO mice |
Description | CARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy) is a hereditary cerebral small-vessel disease caused by loss of function mutations of HTRA1, which is a serine protease with a variety of targets, including extracellular matrix proteins. Htra1-KO mice accumulate matrisome proteins in cerebral blood vessels. We isolated pial arteries (the anterior cerebral artery and the middle cerebral artery) from candesartan-treated and nontreated Htra1-KO mice at 24 months of age. |
HostingRepository | jPOST |
AnnounceDate | 2021-11-16 |
AnnouncementXML | Submission_2022-09-18_02:27:24.181.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Taisuke kato |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | S-carboxamidomethyl-L-cysteine; unknown modification |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2021-01-08 04:51:36 | ID requested | |
1 | 2021-11-15 07:00:04 | announced | |
2 | 2021-11-15 20:19:58 | announced | 2021-11-16: Updated PubMed. |
⏵ 3 | 2022-09-18 02:27:24 | announced | 2022-09-18: Updated FTP location. |
Keyword List
submitter keyword: Pial arteries, Cerebral small-vessel disease, CARASIL, HTRA1-KO, Candesartan |
Contact List
Taisuke Kato | |
---|---|
lab head | |
Taisuke kato | |
contact affiliation | Niigata University |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001052/ |