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PXD023477

PXD023477 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome analysis of brain vessels (the anterior cerebral artery and the middle cerebral artery) from 24-month-old candesartan-treated and nontreated Htra1 KO mice
DescriptionCARASIL (cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy) is a hereditary cerebral small-vessel disease caused by loss of function mutations of HTRA1, which is a serine protease with a variety of targets, including extracellular matrix proteins. Htra1-KO mice accumulate matrisome proteins in cerebral blood vessels. We isolated pial arteries (the anterior cerebral artery and the middle cerebral artery) from candesartan-treated and nontreated Htra1-KO mice at 24 months of age.
HostingRepositoryjPOST
AnnounceDate2021-11-16
AnnouncementXMLSubmission_2022-09-18_02:27:24.181.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterTaisuke kato
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListS-carboxamidomethyl-L-cysteine; unknown modification
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-01-08 04:51:36ID requested
12021-11-15 07:00:04announced
22021-11-15 20:19:58announced2021-11-16: Updated PubMed.
32022-09-18 02:27:24announced2022-09-18: Updated FTP location.
Keyword List
submitter keyword: Pial arteries, Cerebral small-vessel disease, CARASIL, HTRA1-KO, Candesartan
Contact List
Taisuke Kato
lab head
Taisuke kato
contact affiliationNiigata University
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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