PXD023474
PXD023474 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis in the study of the mitochondrial supercomplex assembly |
| Description | Mitochondrial supercomplexes are functionally important, but how supercomplexes being assembled is not known. Mitochondrial Complex I has an important role in the assembly of supercomplex. In this study, we generated a series of cell model with shRNA mediated gene silencing or CRISPR-Cas9 gene knockout technology. We performed a series of mitochondrial proteome analyses in different cell lines with disruption of gene that encodes subunit of Complex I. Also, we performed Co-IP of exogenous TIMMDC1, which was an assembly factor of Complex I. |
| HostingRepository | iProX |
| AnnounceDate | 2021-01-08 |
| AnnouncementXML | Submission_2022-09-21_23:10:48.519.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xianglai Ye |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion; Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2021-01-08 04:06:07 | ID requested | |
| ⏵ 1 | 2022-09-21 23:10:49 | announced |
Publication List
Keyword List
| submitter keyword: mitochondria, supercomplex assembly, mitochondrial proteomics, Co-IP |
Contact List
| Jianxin Lyu | |
|---|---|
| contact affiliation | Wenzhou Medical University |
| contact email | jxlu313@163.com |
| lab head | |
| Xianglai Ye | |
| contact affiliation | Wenzhou Medical University |
| contact email | xlye96@outlook.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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